A primary trend in the US healthcare industry and elsewhere is cost containment. There have been a number of federal and state proposals during the last few years regarding the pricing of pharmaceutical and biopharmaceutical products, limiting coverage and reimbursement for drugs and other medical products, introducing government control and other changes to the healthcare system in the US.

filing / Feb 17, 2026 / receipt

The current administration’s freeze on hiring and new return-to-office policy may disrupt normal operations of federal agencies, including the FDA.

filing / Feb 17, 2026 / receipt

Office Space 28,744 June, 2029 Suzhou, China Office and laboratory space 37,940 October, 2026 Utrecht, Netherlands Office and laboratory space 54,015 July, 2029 We believe that our existing facilities are adequate to meet our current needs and that suitable additional or alternative facilities will be available in the future on commercially reasonable terms to meet our future needs.

filing / Feb 17, 2026 / receipt

Further, the adoption and implementation of any future governmental cost containment or other health reform initiative may result in additional downward pressure on the price that we may receive for any approved product.

filing / Feb 17, 2026 / receipt