(3) Relates to other expenses primarily for software subscriptions and licenses, office expenses, travel and entertainment, director compensation and recruiting fees.

filing / Aug 5, 2026 / receipt

We expect to experience pricing pressures in connection with the sale of any of our product candidates due to the trend toward managed healthcare, the increasing influence of health maintenance organizations, cost containment initiatives and additional legislative changes.

filing / Aug 5, 2026 / receipt

The implementation of cost containment measures or other healthcare reforms may prevent us from being able to generate revenue, attain profitability, or commercialize our products.

filing / Aug 5, 2026 / receipt

Additionally, we operate in a hybrid work environment. As our employees and our business partners’ employees work from home and access our systems remotely, we may be subject to heightened security and privacy risks, including the risks of cyber attacks and privacy incidents.

filing / Aug 5, 2026 / receipt

In July 2025, we implemented our workforce reduction plan. In connection with the workforce reduction plan, we incurred costs of approximately $2.3 million, which were primarily one-time severance benefits.

filing / Aug 5, 2026 / receipt

In connection with the workforce reduction plan, we incurred costs of approximately $2.3 million, which were primarily one-time severance benefits.

filing / Aug 5, 2026 / receipt

(3) Relates to other expenses primarily for software subscriptions and licenses, office expenses, travel and entertainment, director compensation and recruiting fees.

filing / May 13, 2026 / receipt

We expect to experience pricing pressures in connection with the sale of any of our product candidates due to the trend toward managed healthcare, the increasing influence of health maintenance organizations, cost containment initiatives and additional legislative changes.

filing / May 13, 2026 / receipt

The implementation of cost containment measures or other healthcare reforms may prevent us from being able to generate revenue, attain profitability, or commercialize our products.

filing / May 13, 2026 / receipt

Additionally, we operate in a hybrid work environment. As our employees and our business partners’ employees work from home and access our systems remotely, we may be subject to heightened security and privacy risks, including the risks of cyber attacks and privacy incidents.

filing / May 13, 2026 / receipt

In July 2025, we implemented our workforce reduction plan. In connection with the workforce reduction plan, we expect to incur costs of approximately $2.3 million, which are primarily one-time severance benefits.

filing / May 13, 2026 / receipt

In connection with the workforce reduction plan, we expect to incur costs of approximately $2.3 million, which are primarily one-time severance benefits.

filing / May 13, 2026 / receipt