The $0.9 million increase in internal research and development expense is primarily due to a $1.0 million increase in personnel-related expenses due to increased headcount, partially offset by a $0.1 million decrease in other operating costs.

filing / Aug 6, 2026 / receipt

We leased certain office space in San Diego, California, under a non-cancelable operating lease, with a term through December 2025 (the Executive Drive Lease).

filing / Aug 6, 2026 / receipt

On July 22, 2022, we entered into a sublease (the Sublease Agreement) with Origis Operating Services, LLC, (the Sublessee), whereby we agreed to sublease to Sublessee all of the 13,405 rentable square feet of office space currently leased by us under the Executive Drive Lease.

filing / Aug 6, 2026 / receipt

In addition to continuing pressure on prices and cost containment measures, legislative developments at the EU or Member State level may result in significant additional requirements or obstacles that may increase our operating costs.

filing / Aug 6, 2026 / receipt

To the extent that we are no longer eligible to use exemptions from various reporting requirements, we may be unable to realize our anticipated cost savings from these exemptions, which could have a material adverse impact on our operating results.

filing / Aug 6, 2026 / receipt

We will also continue to reimburse each non-employee director for ordinary, necessary, and reasonable out-of-pocket travel expenses to cover in-person attendance at and participation in Board and committee meetings.

filing / Aug 3, 2026 / receipt

This process, which is commonly referred to as “householding”, provides cost savings for companies. Some brokers household proxy materials, delivering a single proxy statement or notice to multiple stockholders sharing an address unless contrary instructions have been received from the affected stockholders.

filing / Aug 3, 2026 / receipt

margin); income (before or after taxes); operating income; operating income after taxes; pre-tax profit; operating cash flow; sales or revenue targets; increases in revenue or product revenue; expenses and cost reduction goals; improvement in or attainment of working capital levels; economic value added (or an equivalent metric); market share; cash flow; cash flow per share; share price performance; debt reduction; c

filing / Aug 3, 2026 / receipt

and Alison Moore, Ph.D., who was appointed by the Board on October 21, 2024.

filing / Aug 3, 2026 / receipt

Laura Stoppel, Ph.D. Director

filing / Aug 3, 2026 / receipt

Elaine Sorg Director

filing / Aug 3, 2026 / receipt

Daniel Baker, M.D. Director

filing / Aug 3, 2026 / receipt