This amount does not include any business travel and expenses reimbursed to office holders. As of December 31, 2025, aggregate options to purchase 1,654,766 ordinary shares outstanding under our Global Share Incentive Plan (2014) (the “ 2014 Plan ”) and Global Share Incentive Plan (2019) (the “ 2019 Plan ”) and 2,157 restricted share units (“ RSUs ”) outstanding under our 2019 Plan were granted to directors and exe

filing / Mar 25, 2026 / receipt

connection with patent applications, travel costs and insurance premiums. We expect that our general and administrative expenses will

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In addition, there is an increasing emphasis on cost containment measures in the United States and other countries, which we expect will continue to increase the pressure on pharmaceutical pricing.

filing / Mar 25, 2026 / receipt

healthcare industries, as well as elsewhere, is cost containment. Government authorities and these third-party payors have attempted to control costs by limiting coverage and the amount of reimbursement for particular medications.

filing / Mar 25, 2026 / receipt

The facility includes office space, laboratories and cGMP clean rooms, in which we manufacture clinical batches to support our clinical trials in Israel and the EU.

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implement internal systems and infrastructure (including, without limitation, hiring of additional personnel, as needed) to develop sales and marketing functions, if and when our product candidate receives applicable regulatory approval;

filing / Mar 25, 2026 / receipt

Matteo Renzi | 51 | Director

filing / Mar 25, 2026 / receipt