In addition, on August 12, 2025, we announced a reduction in force affecting approximately 12% of our workforce. This reduction was part of a tactical operations plan intended to reduce our costs and extend funding of our operations through the end of 2027.

filing / Aug 13, 2026 / receipt

This reduction was part of a tactical operations plan intended to reduce our costs and extend funding of our operations through the end of 2027.

filing / Aug 13, 2026 / receipt

However, this reduction may increase our dependence on the remaining key members of our senior management and executive teams and could result in other unintended consequences, such as the loss of institutional knowledge and expertise, decreased morale or attrition among our remaining employees, and the risk that we may not achieve the anticipated benefits of the reduction in force.

filing / Aug 13, 2026 / receipt

Further, any measures taken by governmental authorities or businesses in response to any public health crisis, such as quarantines, stay-at-home orders or travel restrictions, could adversely affect our business, operations, financial condition, prospects or results of operations by restricting our ability to conduct our clinical trials and research and development activities, and limiting our and our third-party man

filing / Aug 13, 2026 / receipt

The continuing efforts of the government, insurance companies, managed care organizations and other payers of healthcare services to contain or reduce costs of healthcare may adversely affect:

filing / Aug 13, 2026 / receipt

In addition, on August 12, 2025, we announced a reduction in force affecting approximately 12% of our workforce. This reduction was part of a tactical operations plan intended to reduce our costs and extend funding of our operations through the end of 2027.

filing / May 13, 2026 / receipt

This reduction was part of a tactical operations plan intended to reduce our costs and extend funding of our operations through the end of 2027.

filing / May 13, 2026 / receipt

However, this reduction may increase our dependence on the remaining key members of our senior management and executive teams and could result in other unintended consequences, such as the loss of institutional knowledge and expertise, decreased morale or attrition among our remaining employees, and the risk that we may not achieve the anticipated benefits of the reduction in force.

filing / May 13, 2026 / receipt

Further, any measures taken by governmental authorities or businesses in response to any public health crisis, such as quarantines, stay-at-home orders or travel restrictions, could adversely affect our business, operations, financial condition, prospects or results of operations by restricting our ability to conduct our clinical trials and research and development activities, and limiting our and our third-party man

filing / May 13, 2026 / receipt

The continuing efforts of the government, insurance companies, managed care organizations and other payers of healthcare services to contain or reduce costs of healthcare may adversely affect:

filing / May 13, 2026 / receipt

IT Support Specialist | {"ats": "lever", "city": "San Diego", "state": "CA", "job_id": "62f59aff-e5bc-4dbf-a8b9-9a1ce050bf2c", "remote": false, "category": "other", "function": "engineering", "locatio

company_statement / Sep 12, 2026 / receipt

Laboratory Operations Associate I | {"ats": "lever", "city": "San Diego", "state": "CA", "job_id": "17bbb131-01b8-470c-b829-822765c899b1", "remote": false, "category": "other", "function": "operations

company_statement / Aug 22, 2026 / receipt