Earlier this year, we discussed our plan for program prioritization and focused expense management, and we have successfully executed in both areas. First half total operating expenses declined 22% year over year, with G&A expenses for the six-month period ending June 30, 2024, decreasing to approximately $4.3 million, compared to $5.5 million for the same period in 2023. R&D expenses for the six months ended June 30, 2024, also decreased approximately $1.2 million, or 22%, to approximately $3.9 million.

Aug 14, 2024 / receipt, needs a key / Lisa Locklear, CFO | earnings call 2024-08-14 | transcript 192ac438-b871-4c98-9c6f-105cf0ac633b | chars 14141-14650 | segment 14

General and administrative expenses also include public company related expenses; legal fees relating to corporate matters; insurance costs; professional fees for accounting, auditing, tax and consulting services; travel expenses; rent and facility-related expenses, direct depreciation costs and other operating costs.

filing / Aug 12, 2026 / receipt

Locklear and hired her as Chief Financial Officer and Executive Vice President of the Company. Ms. Locklear receives an annual salary of $420,000 and is eligible to receive an annual cash bonus of up to forty -five percent (45%) of her base salary, eighty percent (80%) of which will be based on the achievement of pre -established performance criteria and twenty percent (20%) of which will be based on pre -established

filing / May 20, 2026 / receipt

Cost Reduction Measures & Subsequent Restorative Adjustments Effective on or about February 16, 2026, in connection with the ongoing review of its cash runway and cost structure, and following Board approval, the Company implemented a temporary 50% reduction in the compensation of the Company’s CEO and its Executive Chairman/CSO.

filing / May 20, 2026 / receipt

This process, which is commonly referred to as “householding,” is intended to provide extra convenience for stockholders and cost savings for companies.

filing / May 20, 2026 / receipt