These increases will likely include increased costs related to hiring of additional personnel and fees to outside consultants to support further marketing, legal, tax, planning and accounting activities.

filing / Aug 5, 2026 / receipt

The increased costs will decrease our net income or increase our consolidated net loss and may require us to reduce costs in other areas of our business or increase the prices of our approved medicines and any then-approved product or services.

filing / Aug 5, 2026 / receipt

A trend in the healthcare industry is cost containment. Third-party payors are developing increasingly sophisticated methods of controlling healthcare costs by, among other methods, limiting or preventing (for example via prior authorization, prior therapy or step edit requirements) coverage for particular medications, requiring drug companies to provide them with varying levels of discounts from list prices and/or c

filing / Aug 5, 2026 / receipt

These increases will likely include increased costs related to hiring of additional personnel and fees to outside consultants to support further marketing, legal, tax, planning and accounting activities.

filing / May 6, 2026 / receipt

The increased costs will decrease our net income or increase our consolidated net loss and may require us to reduce costs in other areas of our business or increase the prices of our approved medicines and any then-approved product or services.

filing / May 6, 2026 / receipt

Second Amendment to Office Lease, dated January 13, 2026, by and between the Registrant and Hudson Metro Center, LLC (incorporated by reference to Exhibit 10.15B to the Registrant’s Annual report on Form 10-K, filed with the SEC on February 26, 2026).

filing / May 6, 2026 / receipt

A trend in the healthcare industry is cost containment. Third-party payors are developing increasingly sophisticated methods of controlling healthcare costs by, among other methods, limiting or preventing (for example via prior authorization, prior therapy or step edit requirements) coverage for particular medications, requiring drug companies to provide them with varying levels of discounts from list prices and/or c

filing / May 6, 2026 / receipt

Int’l market expansion

ir_statement / Sep 16, 2026 / receipt

Manager, Vendor Outsourcing (Contract) | {"ats": "greenhouse", "city": null, "state": null, "job_id": "5235767007", "remote": false, "category": "other", "function": "other", "location": "Foster City"

company_statement / Sep 11, 2026 / receipt

Associate Director, Strategic Engagement, West - Genetics, Endo & Metabolics | {"ats": "greenhouse", "city": null, "state": null, "job_id": "5236168007", "remote": true, "category": "other", "function

company_statement / Sep 11, 2026 / receipt

Senior Director, New Product Planning | {"ats": "greenhouse", "city": null, "state": null, "job_id": "5236218007", "remote": false, "category": "other", "function": "other", "location": "Foster City",

company_statement / Sep 11, 2026 / receipt

Senior Director, IT - G&A | {"ats": "greenhouse", "city": null, "state": null, "job_id": "5234034007", "remote": false, "category": "other", "function": "engineering", "location": "Foster City", "job_

company_statement / Sep 10, 2026 / receipt