• $3.2 million decrease in facility costs primarily related to cost savings realized from bringing our vivarium in-house;

filing / Aug 6, 2026 / receipt

• $3.9 million decrease in facility costs primarily related to cost savings realized from bringing our vivarium in-house and due to moving expensed incurred in 2025; and

filing / Aug 6, 2026 / receipt

This was offset by a $3.1 million decrease in personnel expenses driven primarily by fewer personnel-related costs resulting from the workforce reduction announced in May 2025 and a decrease in stock compensation expense of $1.4 million.

filing / Aug 6, 2026 / receipt

• $3.6 million decrease in personnel expenses, driven primarily by fewer personnel-related costs resulting from the workforce reduction announced in May 2025;

filing / Aug 6, 2026 / receipt

This was offset by a $1.6 million decrease in personnel expenses driven primarily by fewer G&A personnel resulting from the workforce reduction announced in May 2025.

filing / May 7, 2026 / receipt

• $3.7 million decrease in personnel expenses, driven primarily by fewer R&D personnel resulting from the workforce reduction announced in May 2025.

filing / May 7, 2026 / receipt

Medical Director, Clinical Development | {"ats": "greenhouse", "city": "Cambridge", "state": "MA", "job_id": "6187978004", "remote": false, "category": "other", "function": "clinical", "location": "Ca

company_statement / Sep 10, 2026 / receipt

Senior Quality Engineering Specialist | {"ats": "greenhouse", "city": "Cambridge", "state": "MA", "job_id": "6184175004", "remote": false, "category": "other", "function": "other", "location": "Cambri

company_statement / Sep 7, 2026 / receipt

Informatics Engineer | {"ats": "greenhouse", "city": "Cambridge", "state": "MA", "job_id": "6140875004", "remote": false, "category": "other", "function": "engineering", "location": "Cambridge, MA", "

company_statement / Aug 11, 2026 / receipt

Scientist II, Discovery & Platform Innovation | {"ats": "greenhouse", "city": "Cambridge", "state": "MA", "job_id": "6119414004", "remote": false, "category": "other", "function": "engineering", "loca

company_statement / Jul 20, 2026 / receipt

Senior Scientist, mRNA Design & Platform Innovation | {"ats": "greenhouse", "city": "Cambridge", "state": "MA", "job_id": "6118859004", "remote": false, "category": "other", "function": "engineering",

company_statement / Jul 17, 2026 / receipt

Senior Scientist / Senior Engineer, LNP Process Development | {"ats": "greenhouse", "city": "Cambridge", "state": "MA", "job_id": "6118870004", "remote": false, "category": "other", "function": "engin

company_statement / Jul 17, 2026 / receipt