● costs of outside consultants, including their fees, stock-based compensation and related travel expenses. 36 Table of Contents We expense research and development costs as incurred.

filing / Aug 13, 2026 / receipt

● a $6.2 million increase in personnel costs, including a $4.3 million increase in salary and benefit related expense, due to an increase in headcount, a $1.7 million increase in stock-based compensation expense, and a $0.2 million increase in external contractor expenses and other personnel costs.

filing / Aug 13, 2026 / receipt

● a $2.3 million increase in personnel costs, including a $1.7 million increase in salary and benefit related expense, primarily due to an increase in headcount to support pre-commercialization efforts, a $0.8 million increase in stock-based compensation expense, offset by a $0.1 million decrease in external contractor expense and other personnel costs, and a $0.1 million decrease in recruiting expense; and

filing / Aug 13, 2026 / receipt

Transition of Chief Financial Officer and Chief Business Officer to Strategic Advisor to the Chairman of the Board Jennifer Fox will be transitioning from her role as the Company’s Chief Financial Officer and Chief Business Officer effective as of September 30, 2026 after which she will be a Strategic Advisor to the Chairman of the Board, first as an employee and then, as of July 1, 2027, as a consultant pursuant t

filing / Aug 13, 2026 / receipt

Jennifer Fox will be transitioning from her role as the Company’s Chief Financial Officer and Chief Business Officer effective as of September 30, 2026 after which she will be a Strategic Advisor to the Chairman of the Board, first as an employee and then, as of July 1, 2027, as a consultant pursuant to a consulting agreement.

filing / Aug 13, 2026 / receipt

● costs of outside consultants, including their fees, stock-based compensation and related travel expenses. We expense research and development costs as incurred.

filing / May 13, 2026 / receipt

These increases will likely include increased costs related to the hiring of additional personnel and fees to outside consultants, among other expenses.

filing / May 13, 2026 / receipt

● a $5.8 million increase in personnel costs, including a $3.9 million increase in salary and benefit related expense, due to an increase in headcount, a $1.5 million increase in stock-based compensation expense, and a $0.4 million increase in external contractor expenses and other personnel costs.

filing / May 13, 2026 / receipt